Faculty of Biotechnology and Food Sciences in Nitra Journal of Microbiology, Biotechnology and Food Sciences 1338-5178 no. 6 vol. 2 2013-06-01 2013-06-01 NUCLEOTIDE COMPARISON OF GDF9 GENE IN INDIAN YAK AND GADDI GOAT: HIGH ALTITUDE LIVESTOCK ANIMALS 2452 2454 EN Lakshya Veer Singh Lakshya Veer Singh S. Jayakumar S. Jayakumar N. Gupta N. Gupta S. P. Dixit S. P. Dixit S. C. Gupta S. C. Gupta The present study was undertaken to characterize exon 1 and exon 2 sequence of one of fecundity genes: GDF9 (Growth differentiation factor 9), in high altitude livestock animal (Yak and Gaddi goat). Six nucleotide differences were identified between sheep (AF078545) and goats (EF446168) in exon 1 and exon 2. Sequencing revealed nine novel single nucleotide mutations in exon 1 and exon 2 of Indian yak that compared with Bos taurus (GQ922451). These results preliminarily showed that the GDF9 gene might be a major gene that influences prolificacy of Gaddi goats and Indian yak.
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