Faculty of Biotechnology and Food Sciences in Nitra Journal of Microbiology, Biotechnology and Food Sciences 1338-5178 no. 4 vol. 4 2015-02-01 2015-02-01 EXPLORATION OF ACTINOMYCETES ENDOPHYTICALLY ASSOCIATED WITH PIPER NIGRUM FOR POTENTIAL BIOACTIVITY 282 286 EN Jasim B. Jasim B. Soumya Rajappan Soumya Rajappan Jyothis Mathew Jyothis Mathew Radhakrishnan E. K. Radhakrishnan E. K. Piper nigrum is well known for its metabolite richness. So endophytic microorganisms that reside within such environments can be expected to have promising biosynthetic potential. The current study identified three endophytic actinomycetes with broad bioactivity which can have applications in natural product related pharmacological research. The Verrucosispora sp identified in the study was found to have promising anticancer and antimicrobial activities and Streptomyces sp. was found to have antioxidant activity. The results obtained are supported by many previous reports and this suggests the isolates obtained in the study to have the possible presence of potential known or novel compounds with broad spectrum of activity.
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