Faculty of Biotechnology and Food Sciences in Nitra Journal of Microbiology, Biotechnology and Food Sciences 1338-5178 vol. 6 2016 2016-08-01 2016-08-01 CYANOGENIC GLYCOSIDES AS A POTENTIAL BIOREGULATOR 743 746 EN Katarína Michalcová Katarína Michalcová Marek Halenár Marek Halenár Adriana Kolesárová Adriana Kolesárová Natural substances which are considered to be a food that provides medical and health benefits are called bioregulator. Bioregulators can be used in medicine for preventing and treating migraine, hypertension, chronic inflammation, and other reaction source diseases. Amygdalin is considered for one of the most important bioregulator. It is a controversial nature cyanogenic glycoside abundant in the seeds of Rosaceae family. The family includes herbs, shrubs, and trees and most species are deciduous, but some are evergreen. In the past few years, has been a renewed interest about distribution of Rosaceae fruits because amygdalin has been used for many years in traditional and alternative medicine. Therefore, it is included in regulatory pathways and processes. Recent data indicate potential regulatory activity of amygdalin in signaling pathways of highly metastatic cells, suggesting that amygdalin might not only be an innovative tool to neutralize metastatic dissemination but also to complement mTOR-inhibitor based regimens.