METABOLIC PARAMETERS CONCENTRATIONS IN BLOOD SERUM OF CZECH PIED BULLS DEPENDING ON SINGLE NUCLEOTIDE POLYMORPHISM OF LEPTIN GENE

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February 2014, vol. 3, special issue 2 (Biotechnology)
pages: 145-147
Article type: Biotechnology of Biotechnology
Abstract: The aim of present study was to test hypothesis, that the leptin gene single nucleotide polymorphism (C/T) giving missense mutation (Arg25Cys) has an effect on concentration of blood serum total cholesterol, beta-hydroxybutyrate and urea in cattle. The experiment were performed in 58 Czech Pied bulls at 240 ± 9 days of age, which were divided in three experimental groups depending on different leptin genotypes (CC, n=28; CT, n=21; TT, n=9). Resulting genotypes in the exon 2 were CC (48.3%), CT (36.2%), and TT (15.5%). There were no differences in serum total cholesterol, urea, beta-hydroxybutyrate concentrations among the genotypes. Based on our results we may assume that analysed SNP of leptin gene have no effect on nutritional status and energy balance in fattened cattle.
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