ASSESSMENT OF BITTER LEAF (Vernonia amygdalina) ON SOME SELECTED PATHOGENIC MICROORGANISMS FROM UNIVERSITY OF ILORIN TEACHING HOSPITAL

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April – May, 2013, vol. 2, no. 5
pages: 2360-2365
Article type: Microbiology of Microbiology
Abstract: Vernonia amygdalina is a medicinal plant which is employed to cure various infections in traditional medicine. The aqueous and ethanolic extracts of this plant were analyzed phytochemically and screened against different microorganisms responsible for various human infections. Phytochemical analysis of the extracts showed the presence of many secondary metabolites including tannins, saponins, alkaloids, flavonoids, phylobatannins, steroids and phenolics. The result shows that the ethanolic extracts showed more antibacterial activity than the aqueous extracts. The extracts displayed potent antimicrobial activity against the test organisms which were Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, Bacillus subtilis, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger, the minimum inhibitory concentration ranges from 2.5-15mg/ml in all the plant extracts. The results confirmed the potency of this plant in treating human infections.

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