IMPACT OF THE T-2 TOXIN AND QUERCETIN ON RABBIT PLASMA LEVELS OF THYROTROPIN AND THYROXINE IN VIVO

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February 2015, vol. 4, special issue 2 (Biotechnology)
pages: 57-59
Article type: Biotechnology of Biotechnology
DOI: 10.15414/jmbfs.2015.4.special2.57-59
Abstract: The aim of this article was to study the effect of quercetin combination with T-2 toxin to secretion of thyrotropin and thyroxine in vivo. The rabbits were divided into the control group (without quercetin and T-2 toxin), and four experimental groups with different doses of quercetin. The thyrotropin (TSH) secretion was not significantly affected by intramuscular application of quercetin and T2-toxin against control group. The secretion of TSH was non-significatly decreased by addition of T2-toxin (group 1), but it was increased after application of quercetin with T2-toxin (groups 2, 3, 4). Significant differences between control group and experimental groups were not observed in thyroxine (T4) secretion. The highest concentration of T4 was observed in group 3 and the lowest in group 2. Our results suggested protective effect of quercetin on TSH secretion.
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