NUCLEOTIDE COMPARISON OF GDF9 GENE IN INDIAN YAK AND GADDI GOAT: HIGH ALTITUDE LIVESTOCK ANIMALS
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June – July, 2013, vol. 2, no. 6
Lakshya Veer Singh, S. Jayakumar, N. Gupta, S. P. Dixit, S. C. Gupta
Biotechnology of Biotechnology
The present study was undertaken to characterize exon 1 and exon 2 sequence of one of fecundity genes: GDF9 (Growth differentiation factor 9), in high altitude livestock animal (Yak and Gaddi goat). Six nucleotide differences were identified between sheep (AF078545) and goats (EF446168) in exon 1 and exon 2. Sequencing revealed nine novel single nucleotide mutations in exon 1 and exon 2 of Indian yak that compared with Bos taurus (GQ922451). These results preliminarily showed that the GDF9 gene might be a major gene that influences prolificacy of Gaddi goats and Indian yak.
GDF9 gene, SNP, Indian yak, gaddi goat
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