EFFECT OF SINGLE DOSE OF T-2 TOXIN ON HAEMATOLOGICAL PARAMETERS OF RABBITS

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Abstracts Special issue on Animal Physiology 2013, vol. 2, Abstracts special issue
pages: 2
Article type: Biotechnology of Biotechnology
Abstract: The aim of the present study was to determine effect of single dose of T-2 toxin on selected haematological parameters of rabbit's blood. Animals were randomly divided into two groups (control C and experimental E). Experimental group of rabbits received intramuscularly T-2 toxin (Romer Labs Division Holding GmbH, Tulln, Austria) at dose 0.08 mg per kg of body weight 72 hours before slaughter. Whole experiment lasted 90 days. In whole blood selected haematological parameters (WBC total white blood cell count, MID medium size cells count, GRA granulocytes count, RBC red blood cell count, HGB haemoglobin, HCT haematocrit, PLT platelet count, MPV mean platelet volume, and PDWc platelet distribution width) were measured using haematology analyser Abacus junior VET (Diatron®, Austria). Single dose of T-2 toxin caused decrease in WBC, MID, GRA, PLT, and PDWc, however without significant differences (P>0.05). Insignificant increase (P>0.05) of RBC, HGB, HCT, and MPV was observed after T-2 toxin treatment. In conclusion, T-2 toxin in single dose 0.08 mg had no harmful effect on rabbits.
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